The bomb exploded outside a post office and killed three children, said ANF, media close to the Kurdish People’s Protection Units (YPG).
Syria’s state news agency SANA also said civilians had been killed, including children.
The Britain-based Syrian Observatory for Human Rights (SOHR) said five civilians were killed in the blast, AFP reports.
No one has claimed responsibility for the attack. However the Islamic State group (ISIS) has claimed several recent bombings and acts of arson.
Although the US-backed and Kurdish-led Syrian Democratic Forces (SDF) seized the last ISIS holdout of Baghouz, eastern Syria in March, militants continue to operate in remote areas.
On Tuesday, the US Department of Defense warned ISIS is “resurging” in Syria.
“Despite losing its territorial ‘caliphate’, the Islamic State in Iraq and Syria (ISIS) solidified its insurgent capabilities in Iraq and was resurging in Syria this quarter,” according to the report.
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