"Terrorist attack via an explosive vehicle — KIA," tweeted Iraq's defense ministry.
The attack took place near one of the markets in al-Qaim district in Anbar province near the Syrian border.
The explosion "martyred one civilian and injured 12 others in addition to injuring four members of security forces."
There was no immediate claim of the attack.
Former Iraqi Prime Minister Haider al-Abadi declared ISIS defeated in December 2017.
The town is situated along the Euphrates River. The Iraqi Counter-Terrorism Service (ICTS), Shiite paramilitias, and local Sunni tribal forces have tried to flush ISIS remnants out of the area since a large offensive in late 2017.
Despite reassurances by Baghdad of border security, analysts fear a US withdrawal from Syria could allow extremist groups to resurface in the river valley.
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